重組人干擾素a-2b

干擾素（IFN）是一個(gè)具有強(qiáng)大抗病毒、抗增殖和免疫調(diào)節(jié)特性的細(xì)胞因子家族，根據(jù)其對(duì)細(xì)胞表面受體的結(jié)合特異性進(jìn)行分類。在人類和小鼠基因組中發(fā)現(xiàn)了十幾種密切相關(guān)的IFN-α亞型，每種亞型共享約80%的氨基酸（aa）序列同源性。人類IFNA2、IFNA2a、IFNA2b和IFNA2c有幾種變體，它們只相差幾個(gè)點(diǎn)突變。成熟人IFNA2b的胞外結(jié)構(gòu)域（ECD）與小鼠IFNA2具有59%的aa序列同一性。

(純度) Purity

≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining).

(內(nèi)毒素) Endotoxin

≤10 EU/mg by the LAL method.

(生物活性) Bioactivity

Measured in a VSV inhibition assay with Wish cells. The ED50 this effect is ≤100 pg/mL, corresponding to a specific bioactivity is ≥2 ×108 units/mg.

(種屬) Species

Human

(表達(dá)系統(tǒng)) Expression System

CHO

(預(yù)測(cè)分子量大小) Mol. Weight

19.2 kDa

(表達(dá)區(qū)間) Expression Region

Cys24-Glu188

(標(biāo)簽) Tag Info

Tag free

(劑型) Formulation

Lyophilized

(溶液) Buffer

PBS, 5% Mannitol and 0.01% Tween 80, pH7.4.

(規(guī)格) Size

10μg/50μg/1mg

(復(fù)溶) Reconstitution

It is recommended to redissolve in sterile deionized water.

(運(yùn)輸) Shipping

The product is shipped with blue ice.

(存儲(chǔ)) Storage & Stability

36 months at -20°C to -80°C in lyophilized state;

6 months at -20°C to -80°C under sterile conditions after reconstitution;

7-10 days at 2°C to 8°C under sterile conditions after reconstitution;

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.?

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